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More people who took semaglutide (86 percent) lost at least five percent of their body weight compared with those on placebo (13 percent)

Weakened pelvic support: Weight loss can reveal pre-existing laxity, especially in postpartum women

In contrast, patients who switched to phentermine after losing at least 20 pounds while on a GLP-1 receptor agonist were more likely to regain weight 1 year after discontinuing the GLP-1 medication, with more than half regaining at least some of their weight

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A major clinical trial called the SELECT trial, published in the New England Journal of Medicine, followed over 17,000 people who were overweight or obese and had existing heart disease

The fix: Space fiber supplements at least 2 hours from other medications